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By Target- 5-HT Receptor
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Results for "
da-6886
" in TargetMol Product Catalog- Inhibitors & Agonists1
da-6886
DA6886, DA 6886
T271171645260-76-9In house
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.
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