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d473

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
JHU-58
T703401632140-61-4
JHU-58 is a novel dipeptide MrgC agonist. JHU-58 inhibited both mechanical and heat hypersensitivity in rats after an L5 spinal nerve ligation (SNL). JHU58 attenuated the evoked excitatory postsynaptic currents in substantia gelatinosa (SG) neurons in wild-type mice, but not in Mrg knockout mice, after peripheral nerve injury.
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6-8 weeks
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D-473
T703411632000-05-5
D-473 is a novel orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
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10-14 weeks
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