d[leu4,lys8] vp acetate

d[Leu4,Lys8]-VP acetate is a selective vasopressin V1b receptor agonist. The Kis for rat, human and mouse V1b receptors are 0.16 nM, 0.52 nM and 0.1.38 nM, respectively. d[Leu4,Lys8]-VP acetate exhibits weak antidiuretic, vasopressor and oxytocic activiti

D[LEU4,LYS8]-VP TFA is a selective agonist for the vasopressin V1b receptor, with Ki values of 0.16 nM for rat, 0.52 nM for human, and 1.38 nM for mouse V1b receptors. This compound exhibits limited antidiuretic, vasopressor, and oxytocic activities in vitro [1] [2].

Selective vasopressin V1B receptor agonist (Ki values are 0.16, 64, 100 and 3800 nM for V1B, oxytocin, V2 and V1A receptors respectively). Displays weak antidiuretic, vasopressor and in vitro oxytocic activities.