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Results for "
cycloguanil d6
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Isotope Products3
- Cycloguanil-D6Chlorguanide triazine D6T10916Cycloguanil-D6 is a dihydrofolate reductase inhibitor, deuterium-labeled Cycloguanil (T5420L).
- $126
SizeQTY - Cycloguanil D6 NitrateChlorguanide triazine D6 NitrateT10915Cycloguanil-D6 Nitrate is a dihydrofolate reductase inhibitor, deuterium-labeled Cycloguanil Nitrate (T69591).
- $392
SizeQTY - Proguanil-D6 hydrochlorideTMIH-0457Proguanil-D6 hydrochloride is a deuterated compound of Proguanil hydrochloride (T4382). Proguanil hydrochloride has a CAS number of 637-32-1. Proguanil Hydrochloride is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, proguanil is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite.
- $653
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