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Results for "
cutamesine
" in TargetMol Product Catalog- Inhibitors & Agonists2
Cutamesine
T36922165377-43-5
Cutamesine (SA4503; AGY-94806), a selective sigma 1 receptor (σ1R) agonist, exhibits high affinity for the σ1R subtype as indicated by (+)-[3H]pentazocine labeling, with an IC50 value of 17.4±1.9 nM. It demonstrates 100-fold lower affinity for the sigma 2 receptor.
- $970
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QTY
Cutamesine dihydrochloride
SA4503 dihydrochloride, SA4503 (dihydrochloride), AGY94806 dihydrochloride
T3597165377-44-6
Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitro and attenuates myocardial hypertrophy in vivo. In a rat model of experimental stroke, it enhances brain plasticity and sensorimotor function.
- $32
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