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cur61414 hydrochloride

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  • Inhibitors & Agonists
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  • CUR61414 hydrochloride
    CUR61414 hydrochloride (334998-36-6 Free base)
    T15019LIn house
    CUR61414 hydrochloride is a potent and cell permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM). CUR61414 hydrochloride is a small-molecule aminoproline class compound. CUR61414 hydrochloride selectively binds to smoothened (Smo, Ki= 44 nM). CUR61414 hydrochloride can induce cancer cells apoptosis without affecting neighboring non-tumor cells.
    • $269
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