cuda

CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR) alpha. CUDA may be valuable for the study of cardiovascular diseases.

CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.

Alcudacigib (Compound 9) TFA is an inhibitor of DGKz. It can be utilized in research related to cancers associated with immune cell activation or cancers resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapies.

Cudarolimab (IBI101) is a human monoclonal antibody and an OX40 (CD134/TNFRSF4) agonist. Cudarolimab activates the OX40 signaling pathway, promoting the proliferation and activation of effector T cells and enhancing T cell-mediated antitumor immune responses, thereby inhibiting tumor growth. Cudarolimab is indicated for use in solid tumor research.