cortisol

Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cytochrome P450 (CYP) isoform CYP11B1. Urinary levels of THS are also elevated in patients with adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA) but are higher in patients with ACC compared to ACA.

Cortisol-1,2-D2 (Standard) is a reference standard of Cortisol-1,2-D2 intended for quantitative analysis, quality control, and related biochemical research applications. Cortisol-1,2-d2 is a deuterated compound of Cortisol. Cortisol has a CAS number of 50-23-7. Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects.

BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).

Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.

Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.

Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilization, and renal calcium excretion, as well as suppressing immune and inflammatory responses.

Cosyntropin (acetate) stimulates the release of corticosteroids such as cortisol from the adrenal gland.

Tetracosactide (Tetracosactrin) (INN) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone.

5-alpha-Hydroxy-Laxogenin is an stress hormone cortisol inhibitor

Hydrocortisone (Standard) is a reference standard for hydrocortisone, suitable for quantitative analysis, quality control, and biochemical experiments. Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenal cortex that activates glucocorticoid receptors.

Hydrocortisone-D3 (Standard) is a reference standard of Hydrocortisone-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Hydrocortisone-d3 is a deuterium-labeled variant of Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone, specifically a glucocorticoid, produced by the adrenal cortex.

Hydrocortisone-D4 (Standard) is a reference standard of Hydrocortisone-D4 intended for quantitative analysis, quality control, and related biochemical research applications. Hydrocortisone-d4 is a deuterated compound of Hydrocortisone. Hydrocortisone has a CAS number of 50-23-7. Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects.

Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol and acts as a specific ligand for intracellular transcortin [1] [2] [3].

Cortisol sulfate sodium (Cortisol 21-sulfate), a metabolite of Cortisol, serves as a specific ligand for intracellular transcortin [1][2][3].

Cortisol-1,2-D2 isol-1,2-D2 is a deuterated compound of Cortisol. Cortisol has a CAS number of 50-23-7. Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects.

Cortisol-D4 Glucuronide (Standard) isol-[D4] Glucuronide (Standard) is a reference standard of Cortisol-[D4] Glucuronide intended for quantitative analysis, quality control, and related biochemical research applications.

Cortisol-9.12.12-D3 (Standard) isol-9.12.12-D3 (Standard) is a reference standard of Cortisol-9.12.12-D3 intended for quantitative analysis, quality control, and related biochemical research applications.

Cortisol-[13C3] (Standard) is a reference standard of Cortisol-[13C3] intended for quantitative analysis, quality control, and related biochemical research applications.

Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a primary metabolite of cortisol, the main glucocorticoid in humans.

Tetrahydrocortisol (Tetrahydrohydrocortisone) is a metabolite of neurosteroids and cortisol, a GABAA receptor antagonist, and also capable of lowering intraocular pressure.

21-Deoxycortisol is a corticosteroid metabolite derived from the adrenal glands, produced by the 11β-hydroxylation of 17α-hydroxyprogesterone. Because it lacks a hydroxyl group at the 21st position, it cannot be further converted into cortisol through normal metabolic pathways. 21-Deoxycortisol is a key biomarker and clinical diagnostic marker for congenital adrenal hyperplasia (CAH); measuring its levels aids in disease screening, diagnosis, and treatment monitoring. As a C11-oxo C21 steroid, 21-deoxycortisol may participate in the “backdoor” pathway of steroid metabolism and is associated with the formation of 11-oxoandrogens and the hyperandrogenic state seen in CAH; therefore, it is also frequently used in research on steroid metabolism and endocrine regulation.

18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.

18-Hydroxycortisol, a cortisol derivative and steroidogenic intermediate, is an endogenous steroid secreted by the adrenal cortex. It serves as a useful biochemical marker in primary aldosteronism (PA) research [1].

Dihydrocortisol is a metabolite of hydrocortisone (cortisol) and a potential mineralocorticoid with inhibitory effects on Human cell line HEK293. It can elevate intraocular pressure by enhancing glucocorticoid activity and induce apoptosis in breast cancer cells.