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cns penetration,brain region

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Lamivudine
GR109714X, BCH-189
T0682134678-17-4
Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
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Lamivudine salicylate
T61427173522-96-8
Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI) that inhibits the reverse transcriptase activity of both HIV-1/2 and hepatitis B virus, while also demonstrating the ability to penetrate the central nervous system [1] [2].
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1-2 weeks
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Lamivudine, (+/-)-trans-
Lamivudine specified impurity B
T25609131086-22-1
Lamivudine, (+/-)-trans- is a reverse transcriptase inhibitor and zalcitabine analog. It is used for the treatment of hepatitis B (HBV) and Human Immunodeficiency Virus Type 1 (HIV-1).
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10-14 weeks
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Lamivudine 13C,15N2
T118141391052-30-4
Lamivudine 13C,15N2, an impurity of Lamivudine (BCH-189), functions as an inhibitor of both HIV-1/2 reverse transcriptase and hepatitis B virus reverse transcriptase, classifying it as a nucleoside reverse transcriptase inhibitor (NRTIs).
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20 days
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Lamivudine triphosphate
3TCTP
T88996143188-53-8
Lamivudine triphosphate (3TCTP), a phosphorylated form of the nucleoside analogue Lamivudine, inhibits the reverse transcriptase of HIV or HBV, blocking viral replication through chain termination. It also acts as an inhibitor of the RdRp activity of the HCVNS5B subunit. Additionally, Lamivudine triphosphate can be incorporated into nascent RNA by SARS-CoV-2 RdRp, thereby preventing mutations in the newly synthesized SARS-CoV-2 RNA.
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10-14 weeks
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Lamivudine-13C-d2
TMID-02852714473-70-6
Lamivudine-13C-d2 the 13C and deuterated compound of Lamivudine. Lamivudine has a CAS number of 134678-17-4. Lamivudine is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
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35 days
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