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cn128 hydrochloride

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CN128 hydrochloride
T93021335282-05-7In house
CN128 hydrochloride, a CN128 derivative, is an orally active and selective iron chelator.CN128 is a novel and orally active hydroxypyridone iron chelator that can be used in the study of β-thalassemia.
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6-8 weeks
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TargetMol
CN128
R-CN128
T850222457170-98-6
CN128, an orally bioavailable iron chelator, features a side chain hydroxy group serving as an alternate sacrificial glucuronidation site to mitigate metabolic inactivation at the 3-hydroxy group. When administered at doses of 150 and 450 µmol/kg, CN128 enhances iron mobilization by 24.8% in a 59Fe-ferritin-loaded rat model of iron overload.
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8-10 weeks
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