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By Target- Anion Exchanger
- COX(1)
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- N-Acetylglucosaminyltransferase(1)
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Results for "
cl-/hco3- exchanger
" in TargetMol Product Catalog- Inhibitors & Agonists2
Talniflumate
Somalgen
T450366898-62-2
Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1 mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl- HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.
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PAT1inh-B01
T815391775330-54-5
PAT1inh-B01, a selective SLC26A6 inhibitor, impedes PAT1 (a Cl- HCO3- exchanger) activity, with an IC50 of 350 nM, effectively inhibiting anion exchange. It also obstructs fluid absorption in the small intestine and is utilized in the study of small intestinal hyposecretory disorders [1].
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