cis-ent-ic351

cis-ent-Tadalafil (cis-ent-IC-351) is a potent and selective PDE5 inhibitor that lowers blood pressure. cis-ent-Tadalafil is a potent and selective PDE5 inhibitor that reduces blood pressure.

Tadalafil hydroxypiperidone is an impurity of Tadalafil -- a phosphodiesterase 5-inhibitor used for the treatment of erectile dysfunction.

cis-Tadalafil (cis-IC-351) is a potent PDE5 inhibitor with an IC50 value of 0.09 μM that can be used to study arterial hypertension.

Tadalafil-13C-d3 the 13C and deuterated compound of Tadalafil. Tadalafil has a CAS number of 171596-29-5. Tadalafil is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

Tadalafil-d3 is a deuterated compound of Tadalafil. Tadalafil has a CAS number of 171596-29-5. Tadalafil is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase (PDE-5), preventing cGMP degradation in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis, thereby causing prolonged muscle relaxation, vasodilation, and enhanced penile erection.