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By Target- Endogenous Metabolite
- Potassium Channel(1)
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Results for "
chloral
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Natural Products2
Penthrichloral
5,5-DI(HYDROXYMETHYL)-2-TRICHLOROMETHYL-1,3-DIOXAN
T2024235684-90-2
Penthrichloral exhibits sedative and hypnotic effects similar to chloral hydrate, but with a more pleasant taste and reduced gastric irritation. Additionally, Penthrichloral is also employed as an adhesive for polyester fibers.
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2,2,2-Trichloroethanol
T37709115-20-8
2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4). It activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery [1]. [1]. Nikhil K Parelkar, et al. 2,2,2-trichloroethanol Activates a Nonclassical Potassium Channel in Cerebrovascular Smooth Muscle and Dilates the Middle Cerebral Artery. J Pharmacol Exp Ther. 2010 Mar;332(3):803-10.
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Thalicminine
TN844116408-77-8
Thalicminine is an alkaloid identified in Thalictrum species. It can induce respiratory stimulation and transient hypotensive effects in dogs. Additionally, Thalicminine prolongs the hypnotic action of chloral hydrate in mice.
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