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chk1in2

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
CHK1-IN-2
T10790912367-45-4
CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).
  • $3,270
3-6 months
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FLT3/CHK1-IN-2
T209231
FLT3/CHK1-IN-2 (Compound 30) is a dual inhibitor targeting FLT3 and CHK1, with IC50 values of 25.63 nM for CHK1, 16.39 nM for FLT3-WT, and 22.80 nM for FLT-D835Y. It displays favorable oral pharmacokinetic properties and kinase selectivity. FLT3/CHK1-IN-2 is applicable in acute myeloid leukemia (AML) research.
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