chitin

Chitin is a large, structural polysaccharide found in the cell walls of fungi, the exoskeletons of insects, and certain hard structures in fish and invertebrates.

Chitin synthase inhibitor 4 is a chitin synthase (CHS) inhibitor with antimicrobial activity.Chitin synthase inhibitor 4 is a CHS-based compound and a candidate fungicide.

Chlorobenzuron, a chitin synthetase inhibitor, functions as an insecticide by inhibiting larval development and pupation.

Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects, acarids and yeasts.

Chitosan (MW 150000) (Deacetylated chitin) is a linear polysaccharide made up of randomly distributed β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine.

Triflumuron is an insecticide belonging to the group of so-called insect growth regulators. It inhibits the synthesis of chitin by the insect larvae, causing the die.

Flucycloxuron ((E)-flucycloxuron) is a chitin synthesis inhibitor used as a pesticide. In insect models, the inhibitor has been shown to affect several reproductive events such as the duration of preovipostion.

Chitosan (Deacetylated chitin) (≥95% deacetylated, viscosity 100-200 mPa.s) is a polysaccharide derived from the deacetylation of chitin, which exhibits antimicrobial activity against various bacteria and fungi.

Chitosan (Deacetylated chitin) (≥90% deacetylated, viscosity 10 mPa.s) is a polysaccharide derived from the deacetylation of chitin and exhibits antimicrobial activity against various bacteria and fungi. Chitosan (≥90% deacetylated, viscosity 10 mPa.s) serves as a versatile biomaterial, applicable in drug delivery, tissue engineering, and wound healing.

Chitosan (Deacetylated chitin) (≥90% deacetylated, viscosity 650-700 mPa.s) is a polysaccharide derived from the deacetylation of chitin, exhibiting antibacterial activity against various bacteria and fungi. With its high degree of deacetylation and specific viscosity, Chitosan can serve as a multifunctional biomaterial in drug delivery, tissue engineering, and wound healing applications.

Chitin synthase inhibitor 2 (compound 2b) is a highly potent inhibitor of chitin synthase, with an IC50 of 0.09 mM and a K i of 0.12 mM. This compound exhibits antimicrobial activity in vitro and demonstrates synergistic or additive effects when combined with fluconazole or polyoxin B [1].

Chitin Synthase Inhibitor 3 (Compound 2d) is a potent inhibitor of chitin synthase, exhibiting an IC50 value of 0.16 mM and demonstrating antifungal activity with a minimum inhibitory concentration (MIC) of 1 μg/mL against Candida albicans [1].

Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor with an IC50 of 0.12 mM, effectively inhibiting drug-resistant fungi variants.

Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal properties, suitable for research on fungal infections.

Chitin synthase inhibitor 7 (compound 9c), a potent inhibitor of chitin synthase (CHS) with an IC50 of 0.37 nM, can be used to study fungal infections.

Chitin synthase inhibitor 6 (compound 9b) is a potent inhibitor of chitin synthase (CHS) with an IC50 of 0.21 mM, exhibiting broad-spectrum antifungal effects against drug-resistant fungi, and is useful for studying fungal infections.

Chitin synthase inhibitor 9, a chitin synthase (CHS) inhibitor, exhibits broad-spectrum antifungal activity and is useful for studies of fungal infections.

Chitin synthase inhibitor 12, a Chitin synthase (CHS) inhibitor, showed excellent CHS inhibition (IC50: 0.16 mM). Chitin synthase inhibitor 12 is also a broad-spectrum antifungal agent resistant to resistant fungal variants (e.g. C. albicans, C. neoformans). Chitin synthase inhibitor 12 can be used to study invasive fungal infections (IFIs).

Chitin synthase inhibitor 11 is a powerful chitin synthase (CHS) inhibitor that markedly reduces CHS activity (IC50: 0.10 mM) and exhibits broad-spectrum in vitro antifungal activity.

Chitin synthase inhibitor 5 effectively blocks chitin synthase, a key enzyme in fungal cell wall formation, with a low IC50 value of 0.14 mM. Chitin synthase inhibitor 5 demonstrates broad-spectrum antifungal activity against Candida albicans, Aspergillus species, and Cryptococcus neoformans.

Chitin Synthase Inhibitor 10, as a potent chitin synthase inhibitor, exhibits remarkable inhibitory activity with an IC50 of 0.11 mM. It also functions as an antifungal agent, demonstrating substantial effectiveness against drug-resistant fungi, including C. albicans and C. neoformans. The compound is useful in researching invasive fungal infections (IFIs) [1].

Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistant fungal strains [1].

Chitin Synthase Inhibitor 13 (compound 12g), a non-competitive antagonist of chitin synthase, demonstrates broad-spectrum antifungal activity and has an inhibition concentration (IC50) of 106.7 μM [1].

Chitosan (Deacetylated chitin) is a biochemical reagent that serves as a biomaterial or organic compound, useful in life science research.