ch2cooh peg9 ch2cooh

CH2COOH-PEG9-CH2COOH, a PEG-based linker for PROTACs, joins two essential ligands and is crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG9-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

Azido-PEG9-CH2COOH is a PROTAC linker of the PEG category utilized in synthesizing PROTAC molecules. This compound functions as a click chemistry reagent, featuring an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAC) with molecules containing an Alkyne group. Additionally, it can participate in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules that have DBCO or BCN groups.