ceftezole

Ceftezole sodium (Falomesin) is a broad-spectrum cephalosporin antibiotic active gram-negative and gram-positive bacteria except for Proteus vulgaris, Pseudomonas aeruginosa, and Serratia marcescens. It has the inhibition of cell wall synthesis via affinity for penicillin-binding proteins. It also inhibits alpha-glucosidase.

Ceftezole is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. It is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria.

Ceftezole, an α-glucosidase inhibitor [IC50: 2.1 μM; Ki: 0.578 μM].

Ceftezole (GR69153) is a broad-spectrum cephalosporin antibiotic that also acts as an α-glucosidase inhibitor. It hinders bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), resulting in cell lysis. Additionally, ceftezole exhibits antidiabetic activity in diabetic mice. It is applicable in research related to antibacterial and antidiabetic studies.