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cdk8in12

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
CDK8-IN-12
T720482613307-67-6In house
CDK8-IN-12 is a selective, potent and orally active inhibitor of CDK8 (Ki: 14 nM) and is an anti-cancer agent. CDK8-IN-12 inhibits GSK-3α, GSK-3β and PCK-θ with Ki of 13 nM, 4 nM and 109 nM respectively. CDK8-IN-12 showed anti-proliferative activity against MV4-11 cells.
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