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(2)
By Target- Akt
- Autophagy(2)
- PKA(2)
- Apoptosis(1)
- S6 Kinase(1)
- mTOR(1)
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Results for "
cct-128930
" in TargetMol Product Catalog- Inhibitors & Agonists2
CCT128930 hydrochloride
CCT128930 hydrochloride(885499-61-6 Free base)
T6303L2453324-32-6
CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50: 168 nM) through the targeting of Met282 of AKT, as well as 20-fold selectivity over p70S6K (IC50: 120 nM).
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