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ccris-93

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  • Inhibitors & Agonists
    2
    TargetMol | All_Pathways
Fazarabine
T6891765886-71-7
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug.
  • $1,520
6-8 weeks
Size
QTY
MDL-100173
T70698142695-09-8
MDL-100173 is a dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitor.
  • $2,420
10-14 weeks
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