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Results for "
ccr1 antagonist 7
" in TargetMol Product Catalog- Inhibitors & Agonists2
CCR1 antagonist 7
T107092446154-74-9
CCR1 antagonist 7 (compound 16r) is a chemokine receptor 1 (CCR1) antagonist with an IC50 of 4 nM [1].
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Vercirnon sodium
GSK-1605786 sodium,CCX282-Bsodium,Traficet-ENsodium
T41016886214-18-2
Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent CCR9 antagonist. It inhibits CCR9-mediated calcium mobilization and chemotaxis in Molt-4 cells with IC50 values of 5.4 nM and 3.4 nM, respectively. Vercirnon sodium demonstrates high selectivity, showing IC50 values exceeding 10 µM for CCR1-12 and CX3CR1-7 receptors. It also inhibits CCL25-directed chemotaxis in both CCR9 splice variants, CCR9A and CCR9B, with IC50 values of 2.8 nM and 2.6 nM, respectively.
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