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(3)
By Target- Epigenetic Reader Domain
- Histone Acetyltransferase(2)
- NF-κB(1)
- c-Myc(1)
- Others(1)
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Results for "
cbp/p300-in-2
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Recombinant Protein1
CBP/p300-IN-2
CBP/EP300-IN-2
T107022158265-96-2
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 with IC50 values of 1.07 nM for CBP/HTRF and 5.96 nM for Myc.
- $2,420
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CBP/p300-IN-22
T210889
CBP/p300-IN-22 is a selective inhibitor of the CBP/EP300 bromodomain, with an IC50 of 4 nM. It exhibits high selectivity for BRD4(1) and reduces cytokine expression induced by TNF-α as well as subsequent immune cell recruitment by inhibiting NF-κB signaling, demonstrating anticancer properties. This compound is applicable for research into rheumatoid arthritis (RA) and other TNF-α-mediated inflammatory diseases.
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CBP/p300-IN-21
T793951065581-69-2
CBP/p300-IN-21 (Compound 5d) is a selective inhibitor of CBP/p300, with IC50 values of 0.07 μM for p300 and 1.755 μM for CBP; it reduces H3K18Ac levels and inhibits the growth of 4T1 tumors in mice [1].
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