canagliflozin

Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM).

Canagliflozin hemihydrate (TA 7284) is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reabsorption (SGLT1 being responsible for the remaining 10%). Blocking this transporter causes up to 119 grams of blood glucose per day to be eliminated through the urine, corresponding to 476 kilocalories.

Canagliflozin impurity 7 is an impurity associated with Canagliflozin.

Canagliflozin impurity 11 is an impurity related to Canagliflozin.

Canagliflozin impurity 9 is a variant impurity of Canagliflozin.

Canagliflozin impurity 5 is an impurity of Canagliflozin.

Canagliflozin impurity 8 is a derivative found within Canagliflozin.

Canagliflozin impurity 10 is an impurity associated with Canagliflozin.

Canagliflozin impurity 79 is an impurity associated with Canagliflozin.

Canagliflozin impurity 4 is an impurity of the compound Canagliflozin.

Canagliflozin impurity 78 is an impurity of Canagliflozin.

Canagliflozin impurity 12 is an impurity associated with Canagliflozin.

Canagliflozin impurity 3 is an impurity associated with Canagliflozin.

Canagliflozin impurity 2 is an impurity of the compound Canagliflozin.

Canagliflozin impurity 1 is a specific impurity related to Canagliflozin.

Canagliflozin impurity 14 is a byproduct of Canagliflozin.

Canagliflozin impurity 14 is a byproduct of the compound Canagliflozin.

Canagliflozin impurity 77 is an impurity of Canagliflozin.

Canagliflozin (Standard) is the standard substance of Canagliflozin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM).

Canagliflozin-[13C6] (Standard) is a reference standard of Canagliflozin-[13C6] intended for quantitative analysis, quality control, and related biochemical research applications.