c188

C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect agai

C188-9 (TTI-101) is an orally administered, highly selective STAT3 SH2 domain inhibitor with a Kd value of 4.7 nM. C188-9 induces apoptosis in AML cell lines and primary samples while inhibiting colony formation in primary AML cells. C188-9 is suitable for studies on tumors, inflammation, and immune evasion.

LOC1886 is a covalent inhibitor of GPX4, with slightly lower potency compared to RSL3 and ML162.

Aspartame (SC-18862), an artificial, non-carbohydrate sweetener, is aspartyl-phenylalanine-1-methyl ester.

DDC18-8A is an amphiphilic dendritic polymer known for its potent antimicrobial and antibiofilm properties.