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  • c-Met/HGFR
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c-met (v1092i)

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
AMG-458
AMG 458
T6378913376-83-7In house
AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
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4-6 weeks
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TargetMol | Inhibitor Sale
Crizotinib
PF-02341066
T1661877399-52-5
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.
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AMG-337
AMG337
T32091173699-31-4
AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM).
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