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  • c-Met/HGFR
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c-met (d1228h)

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
AMG-458
AMG 458
T6378913376-83-7In house
AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
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c-Met-IN-22
T208756
c-Met-IN-22 (compound 51am) is an orally active c-Met inhibitor with an IC50 value of 2.54 nM. It exhibits both antiproliferative and antitumor activities and can induce apoptosis.
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