brd4 ligand linker conjugate 1

BRD4 Ligand-Linker Conjugate 1 is a compound consisting of a ligand and a linker, specifically designed to bind to the target protein BRD4. This conjugate serves as a valuable tool for synthesizing PROTACs, molecules utilized for targeted protein degradation.

Lenalidomide-PEG1-azide is an E3 ligase ligand-linker complex comprising a cereblon ligand and linker, suitable for synthesising PROTACs and click chemistry reactions.

Pomalidomide-PEG1-azide is an E3 ligase ligand-linker conjugate that combines the cereblon ligand based on Pomalidomide with a linker. This compound is instrumental in designing PROTAC BRD4 Degrader-1[1].

Thalidomide-NH-C4-NH2 TFA (compound 29c) is a conjugate composed of an E3 ligase ligand-linker that integrates a Thalidomide-based cereblon ligand and a linker moiety. This compound is used as a component in PROTAC BRD2/BRD4 degrader-1, a highly potent and selective degrader targeting BET proteins BRD4 and BRD2[1].

Boc-Dipiperidine-KLHDC2 ligand 1 is an E3 ubiquitin ligase ligand-linker conjugate, incorporating a KLHDC2 ligand. It is utilized in the synthesis of PROTAC BRD4 Degrader-31.

JQ-1-Azidopropylamine is a Target Protein Ligand-Linker Conjugate, composed of a BRD4 ligand and a PROTAC linker that recruits E3 ligase. It is used in the synthesis of PROTACJY-21.