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By Target- BTK
- IFNAR(1)
- Interleukin(1)
- JAK(1)
- Tyrosine Kinases(1)
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Results for "
bms986165
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Isotope Products1
Deucravacitinib
BMS-986165
T146871609392-27-9
Deucravacitinib is a highly selective, orally bioavailable, allosteric TYK2 inhibitor for the treatment of autoimmune diseases. It blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain, inhibiting IL-12/23 and type I IFN pathways. It selectively binds to the TYK2 pseudokinase (JH2) domain with an IC50 of 1.0 nM.
- $54
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