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bms-955176 hcl

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
BMS-955176 HCl
T699862023808-13-9
GSK-3532795 is a second generation inhibitor of hiv-1 maturation, exhibiting a broader spectrum of antiviral effect in vitro and in clinical studies than the prototypical maturation inhibitor bevirimat
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8-10 weeks
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BMS-955176 HCl hydrate
VF90GZ0UQI, BMS-955176 hydrochloride monohydrate
T2019492023798-97-0
GSK3532795 (also known as BMS-955176) is a potent oral second-generation HIV-1 maturation inhibitor (MI) that has advanced to phase IIb clinical trials. This compound exhibits broad coverage against polymorphic viruses (EC50 < 15 nM, covering common polymorphisms representing 96.5% of HIV-1 subtype B) and demonstrates favorable pharmacokinetic properties in preclinical species.
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