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blm in 1

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
BLM-IN-1
T105572056014-40-3
BLM-IN-1 is a potent inhibitor of Bloom syndrome protein (BLM) with a KD of 1.81 μM and IC50 of 0.95 μM. It induces DNA damage response, apoptosis, and proliferation arrest in cancer cells.
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6-8 weeks
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ATUX-1215
T829382910929-53-0
ATUX-1215, a protein phosphatase 2A (PP2A) activator, diminishes the phosphorylation of ERK, p38, JNK, and Akt, as well as decreases the secretion of IL-12p70, GM-CSF, and IL1α in BLM-treated animals, potentially decelerating lung fibrosis progression [1].
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10-14 weeks
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