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By Target- Calcium Channel
- GPCR19(1)
- Neurokinin receptor(1)
- p38 MAPK(1)
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Results for "
bladder hypersensitivity
" in TargetMol Product Catalog.- Inhibitors & Agonists2
CP-99994
T213211136982-36-0
CP-99994 is a neurokinin 1 (NK-1) receptor antagonist with a Ki of 0.25 nM. It prevents colorectal sensitization under conditions of visceral hypersensitivity and reduces acetic acid-induced colorectal sensitization in a bladder-colon cross-sensitization model. CP-99994 also attenuates neuroglial interactions and MAPK-p38 phosphorylation associated with visceral hypersensitivity.
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