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bj2302

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
FK-143
T70343163136-03-6
FK-143 is a 5-alpha reductase inhibitor.
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8-10 weeks
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BJ-2302
T703441631056-29-5
BJ-2302 is a SRC inhibitor. BJ-2302 effectively suppressed MDA-MB-231 cell invasion (Matrigel invasion assay) and metastasis (chorioallantoic membrane assay xenografted with MDA-MB-231-luc2-tdTomato cancer cells). Additionally, BJ-2302 (1 mg kg) strongly suppressed TNBC cell proliferation in vitro and tumor growth in a xenograft mouse tumor model. The anti-metastatic and anti-tumor effects of BJ-2302 were superior to those of Z-FL-COCHO (1 mg kg) or batimastat (30 mg kg), a pan-MMP inhibitor.
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6-8 weeks
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