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Results for "
bizelesin.
" in TargetMol Product Catalog- Inhibitors & Agonists2
Melafolone
T71032129724-42-1
Melafolone is a natural dual inhibitor of cox-2 and egfr, improving program death 1 (pd-1) checkpoint blockade therapy through normalizing tumor vasculature and pd-l1 downregulation
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Bizelesin
T71034129655-21-6
Bizelesin is a synthetic cyclopropylpyrroloindole antineoplastic antibiotic. Bizelesin binds to the minor groove of DNA and induces interstrand cross-linking of DNA, thereby inhibiting DNA replication and RNA synthesis. Bizelesin also enhances p53 and p21 induction and triggers G2 M cell-cycle arrest, resulting in cell senescence without apoptosis.
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