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By Target- AhR
- Aryl Hydrocarbon Receptor(1)
- CCR(1)
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Results for "
bindarit
" in TargetMol Product Catalog- Inhibitors & Agonists2
Bindarit
AF2838
T6413130641-38-2
Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1 CCL2, MCP-3 CCL7 and MCP-2 CCL8 with anti-inflammatory effects. Bindarit specifically inhibits p65- and p65 p50-induced MCP-1 promoter activation and has no effect on other tested activated promoters.
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BAY-218
AHR antagonist 1
T56222162982-11-6
Bindarit (AF2838)is an aryl hydrocarbon receptor (AHR) antagonist with IC50 of 39.9 nM in the human glioblastoma U87 cell line. BAY-218 inhibition of AhR stimulates pro-inflammatory monocyte and T cell responses in vitro and drives anti-tumor immune responses, leading to reduced tumor growth in vivo.
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