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By Target- HDAC
- Autophagy(1)
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Results for "
belinostat
" in TargetMol Product Catalog- Inhibitors & Agonists3
Belinostat
PXD-101, PXD101, PX105684
T8517866323-14-0
Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
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rac-belinostat
PXD101, PX-105684, NSC726630
T1852414864-00-9
Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
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Belinostat Glucuronide
T705601486471-13-9
Belinostat Glucuronide is the major metabolite of Belinostat. Belinostat is a novel histone deacetylase 3 selective inhibitor that protects β cells from cytokine-induced apoptosis.
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