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begacestat

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  • Inhibitors & Agonists
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  • Begacestat
    WAY-210953, WAY210953, GSI-953, GSI953
    T14525769169-27-9
    Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor (γ-secretase) that inhibits Amyloid-beta production with nanomolar potency, selectively inhibits cleavage of APP in cellular level Notch cleavage assays, reverses situational memory deficits, and can be used to study Alzheimer's disease.
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