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Results for "
be-16627b
" in TargetMol Product Catalog- Inhibitors & Agonists2
BE-16627B
T70834137530-61-1
BE-16627B is a novel metalloproteinase (MP) inhibitor isolated from Streptomyces sp. BE16627B selectively inhibited MPs such as human stromelysin and 92 kD gelatinase. After the cells were cultured with BE16627B for 5 days, BE16627B inhibited MP activity in the primary culture supernatants from synovial cells in a dose-dependent fashion without showing apparent cytotoxicity or affecting the production and secretion of MPs. Its IC50 for active collagenolysis before activation by trypsin was 25 microM.
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Bisindolylmaleimide VII
T70832137592-47-3
Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.
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