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By Target- Bcl-2 Family
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Results for "
bda 366
" in TargetMol Product Catalog- Inhibitors & Agonists2
bda-366 
T67781909226-00-1
BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-apoptotic entity. This compound effectively suppresses lung cancer cell growth[1].
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CYD-2-88
BDA-366 analog
T893581821496-27-8
CYD-2-88 (BDA-366 analog) is an analog of BDA-366 (Bcl2 BH4 antagonist). Administered through intraperitoneal injection at a dosage of 20 mg kg, CYD-2-88 effectively inhibits tumor growth in mice with NSCLC H460 xenografts.
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