babesia

Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.

Chalcone 4 hydrate, an anti-parasite compound, inhibits the growth of Theileria and Babesia.

Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent effective against various microorganisms, including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi (Pneumocystis jirovecii). It is a potent and selective inhibitor of protein tyrosine phosphatases and phosphatase of regenerating liver. Pentamidine dihydrochloride inhibits the parasite Leishmania infantum with an IC50 of 2.5 μM.

Atovaquone-D4 is the deuterium-labeled Atovaquone. Atovaquone (T1491) is a medication used to treat or prevent pneumocystis babesia, malaria, toxoplasmosis, and pneumonia.

Diminazene, an aromatic diamine compound derived from Surfen C, is commonly used in the form of its acetate salt. It exhibits high activity against both Trypanosoma and Babesia spp.

Quinuronium sulfate is a drug used to treat Babesia divergens infections in calves. It did not prevent treated animals from being disease carriers. It may also cause hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH).

ELQ-596, a quinolone derivative, exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-596 attenuates babesiosis in immunosuppressed mice [1].

ELQ-650, a quinolone derivative, exhibits antimicrobial activity against several protozoan parasites, including intraerythrocytic Plasmodium and Babesia, and attenuates babesiosis in immunosuppressed mice [1].

Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL.