azide peg amine (mw 5000)

Azide-PEG-amine (MW 5000) is a polyethylene glycol (PEG)-derived linker compound with azide functionality, primarily utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N3-PEG-NH2 (MW 5000) (Azide-PEG-Amine (MW 5000)) is a heterobifunctional PEG product featuring azide and amine groups at the ends of the PEG chain. This compound serves as a crucial crosslinking agent with a PEG chain. The azide allows for molecular conjugation through chemical reactions, while the amine can react with carboxylic acids or NHS esters.

DBCO-PEG-Amine (MW 5000) (DBCO-PEG-NH2 (MW 5000)) is a polyethylene glycol (PEG) derivative composed of DBCO, PEG units, and an amine group. The amine can react with other chemical groups, such as carboxyl and aldehyde groups, to form stable chemical bonds. Containing a DBCO group, DBCO-PEG-Amine (MW 5000) can participate in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with molecules that have azide groups.