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By Target- Phospholipase
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Results for "
azd 2716
" in TargetMol Product Catalog- Inhibitors & Agonists1
AZD2716
T302551845753-81-2
AZD2716 is a selective secretory phospholipase A2(sPLA2) inhibitor, which can inhibit sPLA2-IIa, sPLA2-V and sPLA2-X, and its IC₅₀ is 10 nM, 40 nM and 400 nM respectively. AZD2716 can reduce the production of pro-inflammatory lipids, thus reducing macrophage activation and foam cell formation, and has been used in the study of atherosclerosis and inflammatory diseases related to sPLA2.
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