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azaphilone-9

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
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    TargetMol | Natural_Products
Azaphilone-9
AZA-9
T729201448460-87-4
Azaphilone-9 (AZA-9) functions as an inhibitor of the HuR-ARE RNA interaction, with an inhibition constant (IC50) of 1.2 μM, by targeting the RNA-binding protein Hu antigen R (HuR). As HuR-RNA interactions play a critical role in stabilizing oncogenic mRNAs within tumors, Azaphilone-9 exhibits potential in inhibiting cancer cell growth and progression.
  • $2,870
10-14 weeks
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Chaetoviridin A
ChaetoviridinA,Chaetoviridin A,Chaetoviridin-A
TN7528128252-98-2
Chaetoviridin A, an azaphilone isolated from Chaetomium globosum, is characterized as 6H-furo[2,3-h]isochromene-6,8(6aH)-dione with substitutions including a chloro group at position 5, a 3-hydroxy-2-methylbutanoyl group at position 9, a methyl group at position 6a, and a 3-methylpent-1-en-1yl group at position 3. It exhibits antifungal activity against plant pathogenic fungi.
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