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By Target- 5-HT Receptor
- Adrenergic Receptor(1)
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Results for "
avn101
" in TargetMol Product Catalog- Inhibitors & Agonists3
AVN-101
T266901061354-48-0
AVN-101 is a highly potent 5-HT7 receptor antagonist with a Ki value of 153 pM. AVN-101 also exhibits considerable affinity for histamine H1 (Ki value of 0.58 nM) and adrenergic α2A, α2B and α2C (Ki values of 0.41-3.6 nM) receptors. AVN-101 has shown good oral bioavailability and brain-blood barrier permeability, low toxicity and reasonable efficacy in animal models of central nervous system diseases.
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3-Quinuclidinyl xanthene-9-carboxylate
T71591102585-08-0
3-Quinuclidinyl xanthene-9-carboxylate is a Muscarinic receptor antagonist.
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AVN-101 free base
T715931025725-91-0
AVN-101 is a very potent 5-HT7 receptor antagonist, with slightly lesser potency toward 5-HT6, 5-HT2A, and 5HT-2C receptors. It is a multi-target drug candidate for the treatment of CNS disorders.
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