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at-7867 dihydrochloride

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at7867 dihydrochloride
T216241431697-86-7
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 Akt2 Akt3 and p70S6K PKA kinase, with IC50 values of 32 nM 17 nM 47 nM and 85 nM 20 nM, respectively. It induces pharmacodynamic changes and inhibits human tumor xenograft growth.
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7-10 days
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TargetMol
AT7867 hydrochloride
T848812624336-89-4
AT7867 hydrochloride is a potent inhibitor of AKT and p70 S6 kinase, displaying oral activity and demonstrating an anticancer effect [1].
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8-10 weeks
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TargetMol
AT7867
T6304857531-00-1
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 values of 32 nM, 17 nM, 47 nM, 85 nM, and 20 nM, respectively, exhibiting little activity outside the AGC kinase family.
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