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By Target- ERK
- PDGFR(1)
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Results for "
astrapterocarpan
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Natural Products1
Methylnissolin
3-Hydroxy-9,10-dimethoxyptercarpan
TN235473340-41-7
Methylnissolin is a natural product isolated from Astragalus membranaceus that inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. It inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibiting the ERK1 2 MAP kinase cascade. It also inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1 2 (ERIC1 2) mitogen-activated protein (MAP) kinases and has antibacterial and anticancer effects.
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TN4561733-40-4
Methylnissolin is a natural product from A. membranaceus.
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