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articaine hydrochloride

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Articaine hydrochloride
Ultracaine, Articaine HCl, Hoe-045
T213123964-57-0
Articaine hydrochloride (Hoe-045), a thiophene-containing local anesthetic, is pharmacologically similar to mepivacaine.
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Articaine
Hoe-045 free base
T7333723964-58-1
Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-gated sodium channels located in the nerve's inner cavity. Furthermore, Articaine mitigates LPS-induced acute kidney injury through the suppression of NF-κB activation and inhibition of the NLRP3 inflammasome pathway.
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1-2 weeks
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