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(2)
By Target- MEK
- MAPK(1)
- Others(2)
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By Target By ResearchField- Cancer(2)
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Results for "
aps-279
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- APS-2-79 hydrochlorideAPS-2-79 HClT67602002381-31-7APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.
- $39
SizeQTY - APS-2-79T700042002381-25-9APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
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