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By Target- Endogenous Metabolite
- FKBP(1)
- Others(1)
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Results for "
ap-219
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- PROTAC Products1
AP219
T36240779282-36-9
AP39 is a compound used to increase hydrogen sulfide (H2S) levels within mitochondria; it consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219, as a control compound for AP39, contains the triphenylphosphonium scaffold but lacks the H2S-releasing portion.
- $113
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AP21998
T214941292606-90-7
AP21998 is a selective ligand for the Fm (mutant FKBP) domain that binds to a single FKBPv. It disrupts FKBP-mediated oligomerization, inhibits the proliferation of transformed myeloid progenitors, and promotes their terminal myeloid differentiation. AP21998 destabilizes aggregates of CAD-hM1 receptor fusion proteins, allowing receptors to exit the endoplasmic reticulum and reach the plasma membrane. AP21998 is applicable in cancer research.
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