amine-peg-thiol

Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker with both an amine group and a thiol group, crucial in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].

H2N-PEG-SH (MW 40000) (Amine-PEG-Thiol (MW 40000)) is a linear heterobifunctional polyethylene glycol derivative that contains both thiol and amine groups. This compound serves as a crucial PEGylated cross-linking or bioconjugation reagent. The thiol or ?SH group selectively reacts with maleimide, OPSS, vinyl sulfone, and surfaces of transition metals (including gold, silver, etc.).

H2N-PEG-SH (MW 20000) (Amine-PEG-Thiol (MW 20000)) is a linear heterobifunctional polyethylene glycol derivative containing thiol and amine groups. This compound serves as a crucial crosslinking or bioconjugation reagent with PEG chains. The thiol group, or ?SH, mercapto group, selectively reacts with maleimide, OPSS, ethene sulfonate, and transition metal surfaces such as gold and silver.

H2N-PEG-SH (MW 10000) (Amine-PEG-Thiol (MW 10000)) is a linear heterobifunctional polyethylene glycol derivative containing thiol and amine groups. This compound serves as a significant PEG-linked crosslinking or bioconjugation reagent. The thiol (?SH) or mercapto group selectively reacts with maleimide, OPSS, vinyl sulfone, and surfaces of transition metals, such as gold and silver.

H2N-PEG-SH (MW 1000) (Amine-PEG-Thiol (MW 1000)) is a linear heterobifunctional polyethylene glycol derivative featuring both thiol and amine groups. This compound serves as a crucial crosslinking or bioconjugation agent with a PEG chain. The thiol or ?SH, also known as a mercapto group, selectively reacts with maleimide, OPSS, vinyl sulfone, and surfaces of transition metals, such as gold and silver.

HS-PEG3-CH2CH2NH2 is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

HS-PEG5-CH2CH2NH2 is a PEG-based linker for PROTACs that connects two essential ligands, vital for forming PROTAC molecules, and facilitates selective protein degradation via the ubiquitin-proteasome system within cells.

HS-PEG7-CH2CH2NH2 is a PEG-based linker for PROTACs, which joins two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amine-PEG6-thiol is a PEG-based PROTAC linker utilized in the synthesis of PROTAC molecules.

Maleimide-PEG4-NHS is a sulfhydryl and amine reactive heterofuncational PEG linker. The chemical bonds formed through Maleimide-PEG4-NHS linker are stable and are not cleavable. The NHS ester reacts with amino groups at pH 7-9 to form stable amide bond wh

Thiol-PEG2-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Stearic acid-PEG-CH2CO2H (MW 3400) is a lipophilic thiol-reactive PEG polymer. The stearic acid segment is effective for encapsulating hydrophobic therapeutic agents, while the PEG chain enhances overall water solubility and biocompatibility. In the presence of activators such as HATU or EDC, the reaction between carboxylic acid (-COOH) and amine (-NH2) forms stable amide bonds through condensation. Reagent grade, for research use only.

Mal-PEG-NH2 TFA (MW 5000) is a linear heterobifunctional PEG product that includes maleimide and ?NH2 groups. The maleimide group has the ability to react with thiol, SH, mercapto, or sulfhydryl groups, while the amine group can interact with carboxylic acids or activated NHS esters.

H2N-PEG-SH (MW 3400) is a linear heterobifunctional polyethylene glycol derivative containing thiol and amine groups. It serves as an important crosslinking or bioconjugation reagent with a PEG chain. The thiol or ?SH group selectively reacts with maleimide, OPSS, vinylsulfone, and transition metal surfaces such as gold and silver.

HOOC-PEG-SH (MW 40000) [HOOC-PEG-Thiol (MW 40000)] is a thiol PEG derivative featuring a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form stable amide bonds or less stable ester bonds. This reactivity allows the conversion of amine or hydroxyl groups into free thiols linked via a linear PEG chain. The resulting thiol group is useful for modifying the surface of gold nanoparticles or participating in other PEGylation reactions. The PEG linker between the thiol and carboxyl groups provides excellent water solubility, flexible linker distance, and increased stability.

H2N-PEG-SH (MW 5000) is a linear heterobifunctional polyethylene glycol derivative containing both thiol and amine groups. H2N-PEG-SH (MW 10000) serves as a crucial crosslinking or bioconjugation agent featuring a PEG chain. The thiol group (?SH), or mercapto group, selectively reacts with maleimide, OPSS, vinyl sulfone, and transition metal surfaces (including gold and silver).

Mal-PEG-NH2 TFA (MW 2000) is a linear heterobifunctional PEG product containing maleimide and NH2 groups. The maleimide group can react with thiol, SH, mercapto, or sulfhydryl groups, while the amine group can react with carboxylic acids or activated NHS esters.

H2N-PEG-SH (MW 2000) is a linear heterobifunctional polyethylene glycol derivative containing thiol and amine groups. It serves as a significant cross-linking or bioconjugation reagent with a PEG chain. The thiol (?SH) or mercapto group selectively reacts with maleimide, OPSS, vinyl sulfone, and transition metal surfaces (such as gold and silver).

Mal-PEG-NH2 TFA (MW 40000) is a linear heterobifunctional PEG compound featuring maleimide and ?NH2 groups. The maleimide group can react with thiol, SH, mercapto, or sulfhydryl groups, while the amine group is reactive with carboxylic acids or activated NHS esters.

FMOC-NH-PEG-SH (MW 5000) (FMOC-NH-PEG-Thiol (MW 5000)) is a PEG derivative containing an Fmoc protecting group and a reactive thiol (-SH) functional group. The thiol group is highly active and can specifically react with various molecules to form stable covalent bonds. Fmoc serves as a common amino-protecting group, shielding the amine from unintended reactions until it is intentionally removed for specific coupling reactions.

Mal-PEG5-amine is a PEG linker that contains a maleimide group and an amine group. The hydrophilic PEG spacer enhances its solubility in aqueous media. The amine group can react with carboxylic acids, activated NHS esters, and carbonyl groups (ketones, aldehydes), while the maleimide group can form covalent bonds with thiol groups, allowing biomolecules to connect via thiol linkage.

Mal-PEG4-amine, a PEG linker containing a maleimide group and an amine group, features a hydrophilic PEG spacer that enhances its solubility in aqueous media. The amine group can react with carboxylic acids, activated NHS esters, and carbonyls (ketones, aldehydes). The maleimide group reacts with thiol groups to form covalent bonds, enabling the conjugation of biomolecules with thiols.