amine peg thiol (mw 3400)

Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker with both an amine group and a thiol group, crucial in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Stearic acid-PEG-CH2CO2H (MW 3400) is a lipophilic thiol-reactive PEG polymer. The stearic acid segment is effective for encapsulating hydrophobic therapeutic agents, while the PEG chain enhances overall water solubility and biocompatibility. In the presence of activators such as HATU or EDC, the reaction between carboxylic acid (-COOH) and amine (-NH2) forms stable amide bonds through condensation. Reagent grade, for research use only.

H2N-PEG-SH (MW 3400) is a linear heterobifunctional polyethylene glycol derivative containing thiol and amine groups. It serves as an important crosslinking or bioconjugation reagent with a PEG chain. The thiol or ?SH group selectively reacts with maleimide, OPSS, vinylsulfone, and transition metal surfaces such as gold and silver.